OUMERE sunscreen is coming: Part 1

We obtain a number of requests for the subsequent product to be added to the OUMERE vary: lip balm, bathe gel, shampoo. However there’s one demand that stands out above all else, and that’s for sunscreen.

And it is no shock {that a} new sunscreen is required available in the market, chemical sunscreens destroy the setting, are banned in some areas, and may trigger eye and pores and skin irritation. Mineral sunscreens are poorly formulated and white soften is a beauty concern.

The white forged is particularly noticeable on these with darker pores and skin tones.

Plus, I have not discovered a “pure” sunscreen that does not put you in danger for pores and skin most cancers. The SPF is usually decrease than marketed. The system incorporates important oils, alcohol, and fragrances that break down your pores and skin cells and make your DNA susceptible to mutations. And so they’re so unhealthy in your pores and skin that you just surrender sporting them and find yourself going out within the solar unprotected.

OUMERE sunscreen is the answer to the sunscreen downside, and it is coming quickly. On this sequence of articles, I’ll present updates on sunscreen, together with the present state of the system, its testing phases, and present challenges.

The system

OUMERE sunscreen will include the pure UV blockers authorised by the FDA: Zinc oxide and titanium dioxide.

Zinc oxide types a bodily block in your pores and skin, as proven on this scanning electron microscope (SEM) picture.

The sunscreen won’t include any chemical inhibitors as a result of its dangerous environmental impression and skill to trigger irritation.

A change of opinion

I’m revising my authentic place that mineral sunscreens shouldn’t be nano for the next causes:

1. There has not been substantial proof to conclusively present that nanoparticles in sunscreen pose a well being hazard.

Present proof has decided that zinc oxide and titanium dioxide nanoparticles don’t attain viable pores and skin cells and trigger no extra irritation or well being downside than their non-nano counterparts.

I additionally perceive that the components in sunscreens must endure in depth overview by the FDA and authorities regulators in a number of nations, and the components that pose vital security issues (as within the case of PABA ) are sometimes withdrawn from the patron market.

There was a number of time and analysis on nanoparticles and nothing conclusive has come up, so I’ve to conclude that there’s not a lot to fret about for the time being.

2. Nano sunscreens look higher on the pores and skin as a result of they don’t give a white forged. Sunscreen solely works in case you put on it, and so as to put on it it’s a must to love the way it appears in your face.

I’ve experimented with each nano and non-nano minerals and the nano variations are significantly better: no white forged, smoother end, and softer really feel.

3. When working with nano or non-nano zinc or titanium dioxide, you’ll obtain powder with medium particle measurement. Because of this the common particle measurement in non-nano zinc is larger than 100nm. Nano zinc is between 80nm and 100. So the distinction just isn’t that large and having 100nm as the edge for what many take into account “secure” could also be extra arbitrary than beforehand thought.

4. Nanoparticles have a better SPF per mg of product used than non-nanoparticles, making them a simpler product.

The inactive (non-pharmaceutical) ingredient a part of the system will include components that improve the consequences of zinc and titanium dioxide, permitting me to place much less of those two components into the system, whereas nonetheless sustaining a excessive SPF. The results of utilizing much less minerals is a much less white forged and a higher need to put on the product.

The inactive components in sunscreen have an effect on the product’s SPF. In case you are in search of varied mineral sunscreens, you can find that you’ll have a spread of SPF and mineral concentrations. Some formulation can have 20% zinc and an SPF of 40, whereas others can have the identical share of zinc and a very completely different SPF. The reason being that the opposite components within the system have an effect on the SPF. I add components that include polyphenols and different natural compounds that improve the protecting results of zinc and titanium dioxide.

FPS

OUMERE sunscreen can be a broad spectrum sunscreen, and can shield in opposition to UV-A (ging) and UV-B (urning) rays. The SPF won’t be lower than 30 or greater than 50. Inside this vary, you get 96.7-98% UV safety. An SPF above 50 provides negligible safety on the expense of chemical substances added to the product.

Present standing and subsequent steps

To market sunscreen, there are extra hurdles to beat than your typical skincare product. Sunscreens are thought of over-the-counter medication as a result of they’re supposed to guard in opposition to pores and skin most cancers, zinc oxide and titanium dioxide are thought of pharmaceutical components, and the entire course of is strictly regulated. by the Meals and Drug Administration. Due to this fact, we have to take further steps to carry the product to the market. The steps are as follows:

1. Kind (present stage)

The steps within the kind contain researching components and writing formulation. This step is full if you create a product that performs and appears to your requirements. I’ve been engaged on the OUMERE sunscreen for 2 years now. I am just about achieved with this step.

2. Take a look at (subsequent step)

The testing part includes sending your ultimate (draft) system to an unbiased sunscreen testing lab that operates beneath FDA tips and requirements. The testing part consists of figuring out the SPF of the product and testing in-vivo with a number of check topics. In vivo assessments present that your sunscreen will be utilized to actual human pores and skin (from a dwelling topic), protects from the solar when utilized on the measured SPF degree, and doesn’t trigger irritation. After this part, stability assessments are carried out to make sure that the sunscreen can keep on a shelf for two years with out dropping its SPF skills or deteriorating.

This step usually takes 2 to six weeks.

The following replace article can be once we attain this milestone.

3. Manufacturing

As soon as the sunscreen has handed the assessments, it is able to be manufactured, which in fact is completed in an FDA-compliant manufacturing facility that focuses on manufacturing sunscreens and operates to the best requirements and the best.

This step usually takes 4-10 weeks

4. Packing

Sunscreen ought to be packaged in a bottle that can lengthen the shelf life to at the very least 2 years. We’ll seemingly go for utterly opaque packaging, as a substitute of the semi-opaque amber packaging that’s discovered in lots of sunscreens. The packaging will stay true to the OUMERE model and can be manufactured from glass which, not like plastic, doesn’t work together or seep into skincare and lengthen shelf life.

The seek for packaging takes a number of months.

As you may see, sunscreen is a problem. However it’s price it. Extra posts to come back.

If you need so as to add your contribution for the subsequent sunscreen, please ship an e-mail to weblog@oumere.com

The references

Holmes, AM, Tune, Z., Moghimi, HR, & Roberts, MS (2016). Relative penetration of zinc oxide and zinc ions in human pores and skin after software of various formulations of zinc oxide. ACS nano, ten(2), 1810-1819.

Lademann, J., Weigmann, H., Rickmeyer, C., Barthelmes, H., Schaefer, H., Mueller, G., & Sterry, W. (2006). A overview of the scientific literature on the security of titanium dioxide or zinc oxide nanoparticles in sunscreens. A us tra li n G over males t. Retrieved from http: // www. tga. govt. to / pdf / overview.

Leite-Silva, VR, Sanchez, WY, Studier, H., Liu, DC, Mohammed, YH, Holmes, AM, … & Grice, JE (2016). Human pores and skin penetration and native results of topical zinc nanoxide after occlusion and barrier alteration. European Journal of Prescribed drugs and Biopharmaceuticals, 104, 140-147.

Newman, MD, Stotland, M., & Ellis, JI (2009). The security of nanoscale particles in titanium dioxide and zinc oxide sunscreens. Journal of the American Academy of Dermatology, 61(4), 685-692.

Vinardell, M., Llanas, H., Marics, L. and Mitjans, M. (2017). Comparative in vitro pores and skin irritation induced by nano and non-nano zinc oxide. Nanomaterials, 7(3), 56.

Origional Post by Platinum Delux

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